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MHC Class I and Integrin Ligation Induce ERK Activation Via an mTORC2-Dependent Pathway

The aim of this study was to characterize the interaction between mTOR and ERK in primary endothelial cells (EC) following MHC class I and integrin ligation. Ligation of MHC class I molecules or integrins on the surface of EC leads to phosphorylation of ERK at Thr202/Tyr204. We utilized small interf...

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Detalhes bibliográficos
Main Authors: Jindra, Peter T., Jin, Yi-Ping, Jacamo, Rodrigo, Rozengurt, Enrique, Reed, Elaine F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376207/
https://ncbi.nlm.nih.gov/pubmed/18312854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.02.093
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