HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca(2+) in human aortic endothelial cells

Following transplantation, HLA class I antibodies targeting donor endothelium stimulate cell proliferation and migration, which contribute to the development of transplant vasculopathy and chronic allograft rejection. Dynamic remodeling of the actin cytoskeleton regulates cell proliferation and migr...

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Main Authors: Ziegler, Mary E., Jin, Yi-Ping, Young, Steven H., Rozengurt, Enrique, Reed, Elaine F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469712/
https://ncbi.nlm.nih.gov/pubmed/22914643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00199.2012
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