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Everolimus Inhibits Anti-HLA I Antibody-Mediated Endothelial Cell Signaling, Migration and Proliferation More Potently than Sirolimus

Antibody (Ab) crosslinking of HLA I molecules on the surface of endothelial cells triggers proliferative and pro-survival intracellular signaling, which is implicated in the process of chronic allograft rejection, also known as transplant vasculopathy. The purpose of this study was to investigate th...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Jin, Yi-Ping, Valenzuela, Nicole M., Ziegler, Mary E., Rozengurt, Enrique, Reed, Elaine F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555744/
https://ncbi.nlm.nih.gov/pubmed/24580843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12669
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