Protein Kinase D Mediates Mitogenic Signaling by G(q)-coupled Receptors through Protein Kinase C-independent Regulation of Activation Loop Ser(744) and Ser(748) Phosphorylation

Rapid protein kinase D (PKD) activation and phosphorylation via protein kinase C (PKC) have been extensively documented in many cell types cells stimulated by multiple stimuli. In contrast, little is known about the role and mechanism(s) of a recently identified sustained phase of PKD activation in...

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Main Authors: Sinnett-Smith, James, Jacamo, Rodrigo, Kui, Robert, Wang, YunZu M., Young, Steven H., Rey, Osvaldo, Waldron, Richard T., Rozengurt, Enrique
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Mechanisms of Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679443/
https://ncbi.nlm.nih.gov/pubmed/19289471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806554200
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