Protein Kinase D1 Mediates Stimulation of DNA Synthesis and Proliferation in Intestinal Epithelial IEC-18 Cells and in Mouse Intestinal Crypts

We examined whether protein kinase D1 (PKD1), the founding member of a new protein kinase family, plays a critical role in intestinal epithelial cell proliferation. Our results demonstrate that PKD1 activation is sustained, whereas that of PKD2 is transient in intestinal epithelial IEC-18 stimulated...

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Main Authors: Sinnett-Smith, James, Rozengurt, Nora, Kui, Robert, Huang, Carlos, Rozengurt, Enrique
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013011/
https://ncbi.nlm.nih.gov/pubmed/21051537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167528
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