Protein Kinase D1 Mediates Stimulation of DNA Synthesis and Proliferation in Intestinal Epithelial IEC-18 Cells and in Mouse Intestinal Crypts

We examined whether protein kinase D1 (PKD1), the founding member of a new protein kinase family, plays a critical role in intestinal epithelial cell proliferation. Our results demonstrate that PKD1 activation is sustained, whereas that of PKD2 is transient in intestinal epithelial IEC-18 stimulated...

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Hlavní autoři: Sinnett-Smith, James, Rozengurt, Nora, Kui, Robert, Huang, Carlos, Rozengurt, Enrique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013011/
https://ncbi.nlm.nih.gov/pubmed/21051537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.167528
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