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CID755673 enhances mitogenic signaling by phorbol esters, bombesin and EGF through a protein kinase D-independent pathway

Recently, CID755673 was reported to act as a highly selective inhibitor of protein kinase D (PKD). In the course of experiments using CID755673, we noticed that it exerted unexpected stimulatory effects on [(3)H]thymidine incorporation and cell cycle progression in Swiss 3T3 cells stimulated by bomb...

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Autors principals: Torres-Marquez, Eugenia, Sinnett-Smith, James, Guha, Sushovan, Kui, Robert, Waldron, Richard T., Rey, Osvaldo, Rozengurt, Enrique
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812606/
https://ncbi.nlm.nih.gov/pubmed/19896460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.11.002
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