Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease

Cushing disease (CD) is a life-threatening disorder attributed to excess pituitary tumor-derived adrenocorticotrophic hormone (ACTH) and adrenal steroid secretion caused by pituitary tumors. Whereas CD was first described in 1932, the underlying genetic basis driving tumor growth and ACTH secretion...

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Autori principali: Du, Li, Bergsneider, Marvin, Mirsadraei, Leili, Young, Steven H., Jonker, Johan W., Downes, Michael, Yong, William H., Evans, Ronald M., Heaney, Anthony P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666748/
https://ncbi.nlm.nih.gov/pubmed/23653479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306182110
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