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Targeting the ERK pathway for the treatment of Cushing's disease
We recently demonstrated that the orphan nuclear receptor testicular receptor 4 (TR4) is a potent regulator of corticotroph tumor growth and hormone secretion. The Ras/Raf/MEK/ERK pathway is commonly overactivated in human tumors and we have demonstrated that corticotroph tumor TR4 is activated by E...
Bewaard in:
Gepubliceerd in: | Oncotarget |
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Hoofdauteurs: | , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Impact Journals LLC
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342466/ https://ncbi.nlm.nih.gov/pubmed/27708250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12381 |
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