Additional In Vitro and In Vivo Evidence for SecA Functioning as Dimers in the Membrane: Dissociation into Monomers Is Not Essential for Protein Translocation in Escherichia coli

Por Wang, Hongyun, Na, Bing, Yang, Hsiuchin, Tai, Phang C.
Publicado em 2008

Characterization of the minimal length of functional SecA in Escherichia coli

Por Na, Bing, You, Zhipeng, Yang, Hsiuchin, Tai, Phang C.
Publicado no Biochem Biophys Res Commun (2014)

SecAAA trimer is fully functional as SecAA dimer in the membrane: Existence of higher oligomers?

Por Wang, Hongyun, Ma, Yamin, Hsieh, Ying-Hsin, Yang, Hsiuchin, Li, Minyong, Wang, Binghe, Tai, Phang C.
Publicado em 2014

The First Low µM SecA Inhibitors

Por Chen, Weixuan, Huang, Ying-ju, Gundala, Sushma Reddy, Yang, Hsiuchin, Li, Minyong, Tai, Phang C., Wang, Binghe
Publicado em 2010

Fluorescein analogs inhibit SecA ATPase: the first sub-µM inhibitor of bacterial protein translocation

Por Huang, Ying-Ju, Wang, Hongyun, Gao, Fen-Biao, Li, Minyong, Yang, Hsiuchin, Wang, Binghe, Tai, Phang C.
Publicado em 2012

Ring-like pore structures of SecA: Implication for bacterial protein-conducting channels

Por Wang, Hong-Wei, Chen, Yong, Yang, Hsiuchin, Chen, Xianchuan, Duan, Ming-Xing, Tai, Phang C., Sui, Sen-Fang
Publicado em 2003

Phospholipids Induce Conformational Changes of SecA to Form Membrane-Specific Domains: AFM Structures and Implication on Protein-Conducting Channels

Por You, Zhipeng, Liao, Meijiang, Zhang, Hao, Yang, Hsiuchin, Pan, Xijian, Houghton, John E., Sui, Sen-fang, Tai, Phang C.
Publicado em 2013

Specificity of SecYEG for PhoA precursors and SecA homologs on SecA protein-conducting channels

Por Zhang, Hao, Hsieh, Ying-hsin, Lin, Bor-ruei, Yu, Liyan, Yang, Hsiuchin, Jiang, Chun, Sui, Sen-fang, Tai, Phang C.
Publicado em 2013

Mechanisms of Rose Bengal inhibition on SecA ATPase and ion channel activities

Por Hsieh, Ying-Hsin, Huang, Ying-Ju, Jin, Jin-Shan, Yu, Liyan, Yang, Hsiuchin, Jiang, Chun, Wang, Binghe, Tai, Phang C.
Publicado no Biochem Biophys Res Commun (2014)

Evaluation of Small Molecule SecA Inhibitors against Methicillin-Resistant Staphylococcus aureus

Por Jin, Jinshan, Cui, Jianmei, Chaudhary, Arpana Sagwal, Hsieh, Ying-Hsin, Damera, Krishna, Zhang, Hao, Yang, Hsiuchin, Wang, Binghe, Tai, Phang C.
Publicado no Bioorg Med Chem (2015)

SecA Alone Can Promote Protein Translocation and Ion Channel Activity: SecYEG INCREASES EFFICIENCY AND SIGNAL PEPTIDE SPECIFICITY

Por Hsieh, Ying-hsin, Zhang, Hao, Lin, Bor-ruei, Cui, Ningren, Na, Bing, Yang, Hsiuchin, Jiang, Chun, Sui, Sen-fang, Tai, Phang C.
Publicado em 2011

Dissecting structures and functions of SecA-only protein-conducting channels: ATPase, pore structure, ion channel activity, protein translocation, and interaction with SecYEG/SecDF...

Por Hsieh, Ying-hsin, Huang, Ying-ju, Zhang, Hao, Liu, Qian, Lu, Yang, Yang, Hsiuchin, Houghton, John, Jiang, Chun, Sui, Sen-Fang, Tai, Phang C.
Publicado no PLoS One (2017)

Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram-negative Bacteria

Por Jin, Jinshan, Hsieh, Ying-Hsin, Cui, Jianmei, Damera, Krishna, Dai, Chaofeng, Chaudhary, Arpana S., Zhang, Hao, Yang, Hsiuchin, Cao, Nannan, Jiang, Chun, Vaara, Martti, Wang, Binghe, Tai, Phang C.
Publicado no ChemMedChem (2016)