Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram-negative Bacteria

With the wide-spread emergence of drug resistance, there is an urgent need to search for new antimicrobials, especially those against Gram-negative bacteria. Along this line, the identification of viable targets is a critical first step. SecA is a protein translocase and is commonly believed to be a...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Jin, Jinshan, Hsieh, Ying-Hsin, Cui, Jianmei, Damera, Krishna, Dai, Chaofeng, Chaudhary, Arpana S., Zhang, Hao, Yang, Hsiuchin, Cao, Nannan, Jiang, Chun, Vaara, Martti, Wang, Binghe, Tai, Phang C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5189635/
https://ncbi.nlm.nih.gov/pubmed/27753464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600421
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