Evaluation of Small Molecule SecA Inhibitors against Methicillin-Resistant Staphylococcus aureus

Due to the emergence and rapid spread of drug resistance in bacteria, there is an urgent need for the development of novel antimicrobials. SecA, a key component of the general bacterial secretion system required for viability and virulence, is an attractive antimicrobial target. Earlier we reported...

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Publicado no:Bioorg Med Chem
Main Authors: Jin, Jinshan, Cui, Jianmei, Chaudhary, Arpana Sagwal, Hsieh, Ying-Hsin, Damera, Krishna, Zhang, Hao, Yang, Hsiuchin, Wang, Binghe, Tai, Phang C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661110/
https://ncbi.nlm.nih.gov/pubmed/26432604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.09.027
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