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Phospholipids Induce Conformational Changes of SecA to Form Membrane-Specific Domains: AFM Structures and Implication on Protein-Conducting Channels

SecA, an essential component of the Sec machinery, exists in a soluble and a membrane form in Escherichia coli. Previous studies have shown that the soluble SecA transforms into pore structures when it interacts with liposomes, and integrates into membranes containing SecYEG in two forms: SecA(S) an...

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Detalhes bibliográficos
Main Authors: You, Zhipeng, Liao, Meijiang, Zhang, Hao, Yang, Hsiuchin, Pan, Xijian, Houghton, John E., Sui, Sen-fang, Tai, Phang C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745498/
https://ncbi.nlm.nih.gov/pubmed/23977317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072560
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