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Fluorescein analogs inhibit SecA ATPase: the first sub-µM inhibitor of bacterial protein translocation
SecA is a central component of the general secretion system that is essential for bacterial growth and thus an ideal target for the development of antimicrobial agents. A series of fluorescein analogs were first screened against the ATPase activity using the truncated unregulated SecA catalytic doma...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483595/ https://ncbi.nlm.nih.gov/pubmed/22354575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100594 |
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