Novel Functional Complexity of Polycystin-1 by GPS Cleavage In Vivo: Role in Polycystic Kidney Disease

le Kurbegovic, Almira, Kim, Hyunho, Xu, Hangxue, Yu, Shengqiang, Cruanès, Julie, Maser, Robin L., Boletta, Alessandra, Trudel, Marie, Qian, Feng
Foilsithe 2014

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations

le Qian, Feng, Boletta, Alessandra, Bhunia, Anil K., Xu, Hangxue, Liu, Lijuan, Ahrabi, Ali K., Watnick, Terry J., Zhou, Fang, Germino, Gregory G.
Foilsithe 2002

Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure

le Yu, Shengqiang, Hackmann, Karl, Gao, Jianggang, He, Xiaobing, Piontek, Klaus, García González, Miguel A., Menezes, Luis F., Xu, Hangxue, Germino, Gregory G., Zuo, Jian, Qian, Feng
Foilsithe 2007

A novel model of autosomal recessive polycystic kidney questions the role of the Fibrocystin C-terminus in disease mechanism

le Outeda, Patricia, Menezes, Luis, Hartung, Erum A., Bridges, Stacey, Zhou, Fang, Zhu, Xianjun, Xu, Hangxue, Huang, Qiong, Yao, Qin, Qian, Feng, Germino, Gregory G, Watnick, Terry
Foilsithe in Kidney Int (2017)

Defective Glucose Metabolism in Polycystic Kidney Disease Identifies A Novel Therapeutic Paradigm

le Rowe, Isaline, Chiaravalli, Marco, Mannella, Valeria, Ulisse, Valeria, Quilici, Giacomo, Pema, Monika, Song, Xuewen W., Xu, Hangxue, Mari, Silvia, Qian, Feng, Pei, York, Musco, Giovanna, Boletta, Alessandra
Foilsithe in Nat Med (2013)

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism

le Kim, Hyunho, Xu, Hangxue, Yao, Qin, Li, Weizhe, Huang, Qiong, Outeda, Patricia, Cebotaru, Valeriu, Chiaravalli, Marco, Boletta, Alessandra, Piontek, Klaus, Germino, Gregory G., Weinman, Edward J., Watnick, Terry, Qian, Feng
Foilsithe in Nat Commun (2014)

A Pkd1-Fbn1 Genetic Interaction Implicates TGF-β Signaling in the Pathogenesis of Vascular Complications in Autosomal Dominant Polycystic Kidney Disease

le Liu, Dongyan, Wang, Connie J., Judge, Daniel P., Halushka, Marc K., Ni, Jie, Habashi, Jennifer P., Moslehi, Javid, Bedja, Djahida, Gabrielson, Kathleen L., Xu, Hangxue, Qian, Feng, Huso, David, Dietz, Harry C., Germino, Gregory G., Watnick, Terry
Foilsithe 2014