Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism

Primary cilia contain specific receptors and channel proteins that sense the extracellular milieu. Defective ciliary function causes ciliopathies such as autosomal dominant polycystic kidney disease (ADPKD). However, little is known about how large ciliary transmembrane proteins traffic to the cilia...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kim, Hyunho, Xu, Hangxue, Yao, Qin, Li, Weizhe, Huang, Qiong, Outeda, Patricia, Cebotaru, Valeriu, Chiaravalli, Marco, Boletta, Alessandra, Piontek, Klaus, Germino, Gregory G., Weinman, Edward J., Watnick, Terry, Qian, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237283/
https://ncbi.nlm.nih.gov/pubmed/25405894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6482
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