Diverse Molecular Targets for Chalcones with Varied Bioactivities

Por Zhou, Bo, Xing, Chengguo
Publicado no Med Chem (Los Angeles) (2015)

Chalcone-based inhibitors against hypoxia-inducible factor 1 – Structure activity relationship studies

Por Srinivasan, Balasubramanian, Johnson, Thomas E., Xing, Chengguo
Publicado em 2010

Identification of methysticin as a potent and non-toxic NF-κB inhibitor from kava, potentially responsible for kava's chemopreventive activity

Por Shaik, Ahmad Ali, Lee Hermanson, David, Xing, Chengguo
Publicado em 2009

Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1

Por Xing, Chengguo, Wang, Liangyou, Tang, XiaoHu, Sham, Yuk Y
Publicado em 2006

Overexpression of Mcl-1 Confers Multidrug Resistance, Whereas Topoisomerase IIβ Downregulation Introduces Mitoxantrone-Specific Drug Resistance in Acute Myeloid Leukemia

Por Hermanson, David L., Das, Sonia G., Li, Yunfang, Xing, Chengguo
Publicado em 2013

Measuring the Chemical and Cytotoxic Variability of Commercially Available Kava (Piper methysticum G. Forster)

Por Martin, Amanda C., Johnston, Ed, Xing, Chengguo, Hegeman, Adrian D.
Publicado no PLoS One (2014)

Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations

Por Lü, Junxuan, Zhang, Jinhui, Li, Li, Jiang, Cheng, Xing, Chengguo
Publicado no Curr Pharmacol Rep (2015)

Development of dimeric modulators for anti-apoptotic Bcl-2 proteins

Por Wang, Liangyou, Kong, Fansen, Kokoski, Candis, Andrews, David W., Xing, Chengguo
Publicado em 2007

A Novel SERCA Inhibitor Demonstrates Synergy with Classic SERCA Inhibitors and Targets Multidrug-Resistant AML

Por Bleeker, Nicholas P., Cornea, Razvan L., Thomas, David D., Xing, Chengguo
Publicado em 2013

Flavokawains A and B in Kava, Not Dihydromethysticin, Potentiate Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice

Por Narayanapillai, Sreekanth C., Leitzman, Pablo, O’Sullivan, M. Gerard, Xing, Chengguo
Publicado em 2014

Identification of GAPDH as a protein target of the saframycin antiproliferative agents

Por Xing, Chengguo, LaPorte, Jacob R., Barbay, Joseph K., Myers, Andrew G.
Publicado em 2004

WL-276, an antagonist against Bcl-2 proteins, overcomes drug resistance and suppresses prostate tumor growth

Por Wang, Liangyou, Sloper, Daniel T., Addo, Sadiya N., Tian, Defeng, Slaton, Joel W., Xing, Chengguo
Publicado em 2008

sHA 14-1, a stable and ROS-free antagonist against anti-apoptotic Bcl-2 proteins, bypasses drug resistances and synergizes cancer therapies in human leukemia cell

Por Tian, Defeng, Das, Sonia Goutam Kumar, Doshi, Jignesh M., Peng, Jun, Lin, Jialing, Xing, Chengguo
Publicado em 2007

Single Oral Dose Pharmacokinetics of Decursin and Decursinol Angelate in Healthy Adult Men and Women

Por Zhang, Jinhui, Li, Li, Hale, Thomas W., Chee, Wayne, Xing, Chengguo, Jiang, Cheng, Lü, Junxuan
Publicado no PLoS One (2015)

Cytochrome P450 isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica

Por ZHANG, Jinhui, LI, Li, TANG, Suni, HALE, Thomas W., XING, Chengguo, JIANG, Cheng, LÜ, Junxuan
Publicado no Am J Chin Med (2015)

The Effect of Tobacco Smoking on Musculoskeletal Health: A Systematic Review

Por Ahmad M. AL-Bashaireh, Linda G. Haddad, Michael Weaver, Debra Lynch Kelly, Xing Chengguo, Saunjoo Yoon
Publicado em 2018-01-01

Ethyl 2-amino-6-(3,5-dimethoxyphenyl)-4-(2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate (CXL017) – a novel scaffold that re-sensitizes multidrug resistant leukemia cells to chemoth...

Por Das, Sonia G., Hermanson, David L., Bleeker, Nicholas, Lowman, Xazmin, Li, Yunfang, Kelekar, Ameeta, Xing, Chengguo
Publicado em 2012

Pyranocoumarin tissue distribution, and plasma metabolome and prostate transcriptome impacts of sub-chronic exposure to Korean Angelica supplement in mice

Por ZHANG, Jinhui, LI, Li, TANG, Suni, ZHANG, Yong, MARKIEWSKI, Maciej, XING, Chengguo, JIANG, Cheng, LÜ, Junxuan
Publicado no Am J Chin Med (2016)

Direct detection of SERCA calcium transport and small-molecule inhibition in giant unilamellar vesicles

Por Bian, Tengfei, Autry, Joseph M., Casemore, Denise, Li, Ji, Thomas, David D., He, Gaohong, Xing, Chengguo
Publicado no Biochem Biophys Res Commun (2016)

Inhibition of mitogen activated protein kinases increases the sensitivity of A549 lung cancer cells to the cytotoxicity induced by a kava chalcone analog

Por Warmka, Janel K., Solberg, Eric L., Zeliadt, Nicholette A., Srinivasan, Balasubramanian, Charlson, Aaron T., Xing, Chengguo, Wattenberg, Elizabeth V.
Publicado em 2012