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Cytochrome P450 isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica
We have shown that the in vitro hepatic microsomal metabolism of pyranocoumarin compound decursinol angelate (DA) to decursinol (DOH) exclusively requires cytochrome P450 enzymes (CYP) whereas the conversion of its isomer decursin (D) to DOH can be mediated by CYP and esterase(s). To provide insight...
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| Publicado no: | Am J Chin Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4872390/ https://ncbi.nlm.nih.gov/pubmed/26394652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S0192415X1550069X |
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