Restoration of Normal Cerebral Oxygen Consumption with Rapamycin Treatment in a Rat Model of Autism–Tuberous Sclerosis

Por Chi, Oak Z., Wu, Chang-Chih, Liu, Xia, Rah, Kang H., Jacinto, Estela, Weiss, Harvey R.
Publicado no Neuromolecular Med (2015)

mTOR complex 2 modulates αβT-cell receptor processing and surface expression during thymocyte development ()

Por Chou, Po-Chien, Oh, Won Jun, Wu, Chang-Chih, Moloughney, Joseph, Rüegg, Markus, Hall, Michael N., Jacinto, Estela, Werlen, Guy
Publicado em 2014

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

Por Oh, Won Jun, Wu, Chang -chih, Kim, Sung Jin, Facchinetti, Valeria, Julien, Louis -André, Finlan, Monica, Roux, Philippe P, Su, Bing, Jacinto, Estela
Publicado em 2010

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8

Por Kim, Sung Jin, DeStefano, Michael A., Oh, Won Jun, Wu, Chang-chih, Vega-Cotto, Nicole M., Finlan, Monica, Liu, Dou, Su, Bing, Jacinto, Estela
Publicado em 2012

mTORC2 responds to glutamine catabolite levels to modulate the hexosamine biosynthesis enzyme GFAT1

Por Moloughney, Joseph G., Kim, Peter K., Vega-Cotto, Nicole M., Wu, Chang-Chih, Zhang, Sisi, Adlam, Matthew, Lynch, Thomas, Chou, Po-Chien, Rabinowitz, Joshua D., Werlen, Guy, Jacinto, Estela
Publicado no Mol Cell (2016)

mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation

Por Moloughney, Joseph G., Vega-Cotto, Nicole M., Liu, Sharon, Patel, Chadni, Kim, Peter K., Wu, Chang-chih, Albaciete, Danielle, Magaway, Cedric, Chang, Austin, Rajput, Swati, Su, Xiaoyang, Werlen, Guy, Jacinto, Estela
Publicado no J Biol Chem (2018)

Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media

Por Bauler, Matthew, Roberts, Jessica K., Wu, Chang-Chih, Fan, Baochang, Ferrara, Francesca, Yip, Bon Ham, Diao, Shiyong, Kim, Young-In, Moore, Jennifer, Zhou, Sheng, Wielgosz, Matthew M., Ryu, Byoung, Throm, Robert E.
Publicado no Mol Ther Methods Clin Dev (2019)

mTORC1-Mediated Inhibition of 4EBP1 is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma

Por Wu, Chang-Chih, Hou, Shirui, Orr, Brent A., Kuo, Bryan R., Youn, Yong Ha, Ong, Taren, Roth, Fanny, Eberhart, Charles G., Robinson, Giles W., Solecki, David J., Taketo, Makoto M., Gilbertson, Richard J., Roussel, Martine F., Han, Young-Goo
Publicado no Dev Cell (2017)