mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation

The mechanistic target of rapamycin (mTOR) controls metabolic pathways in response to nutrients. Recently, we have shown that mTOR complex 2 (mTORC2) modulates the hexosamine biosynthetic pathway (HBP) by promoting the expression of the key enzyme of the HBP, glutamine:fructose-6-phosphate aminotran...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Moloughney, Joseph G., Vega-Cotto, Nicole M., Liu, Sharon, Patel, Chadni, Kim, Peter K., Wu, Chang-chih, Albaciete, Danielle, Magaway, Cedric, Chang, Austin, Rajput, Swati, Su, Xiaoyang, Werlen, Guy, Jacinto, Estela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200946/
https://ncbi.nlm.nih.gov/pubmed/30201609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003991
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados