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A two-pore channel protein required for regulating mTORC1 activity on starvation

BACKGROUND: Two-pore channels (TPCs) release Ca(2+) from acidic intracellular stores and are implicated in a number of diseases, but their role in development is unclear. The social amoeba Dictyostelium discoideum proliferates as single cells that aggregate to form a multicellular organism on starva...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Chang, Fu-Sheng, Wang, Yuntao, Dmitriev, Phillip, Gross, Julian, Galione, Antony, Pears, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6977259/
https://ncbi.nlm.nih.gov/pubmed/31969153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0735-4
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