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mTOR complex 2 modulates αβT-cell receptor processing and surface expression during thymocyte development ()

An efficient immune response relies on the presence of T-cells expressing a functional T-cell receptor (TCR). While the mechanisms generating TCR diversity for antigenic recognition are well defined, what controls its surface expression is less known. Here we found that deletion of the mTORC2 compon...

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Detalhes bibliográficos
Main Authors: Chou, Po-Chien, Oh, Won Jun, Wu, Chang-Chih, Moloughney, Joseph, Rüegg, Markus, Hall, Michael N., Jacinto, Estela, Werlen, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108500/
https://ncbi.nlm.nih.gov/pubmed/24981454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303162
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