Glutamate-gated Chloride Channels

Por Wolstenholme, Adrian J.
Publicado em 2012

Ion channels and receptor as targets for the control of parasitic nematodes

Por Wolstenholme, Adrian J.
Publicado em 2011

Anthelmintics – From Discovery to Resistance

Por Wolstenholme, Adrian J., Martin, Richard J.
Publicado no Int J Parasitol Drugs Drug Resist (2014)

Anthelmintics: From discovery to resistance II (San Diego, 2016)

Por Martin, Richard J., Wolstenholme, Adrian J., Caffrey, Conor R.
Publicado no Int J Parasitol Drugs Drug Resist (2016)

GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit from Caenorhabditis elegans

Por Horoszok, Lucy, Raymond, Valérie, Sattelle, David B, Wolstenholme, Adrian J
Publicado em 2001

Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion

Por Lavender, Verna, Chong, Setareh, Ralphs, Katherine, Wolstenholme, Adrian J., Reaves, Barbara J.
Publicado em 2008

FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways

Por Feng, Ying, Williams, Barnabas G., Koumanov, Françoise, Wolstenholme, Adrian J., Holman, Geoffrey D.
Publicado em 2013

An Ivermectin-Sensitive Glutamate-Gated Chloride Channel from the Parasitic Nematode Haemonchus contortus

Por McCavera, Samantha, Rogers, Adrian T., Yates, Darran M., Woods, Debra J., Wolstenholme, Adrian J.
Publicado em 2009

Glutamate-Gated Chloride Channels of Haemonchus contortus Restore Drug Sensitivity to Ivermectin Resistant Caenorhabditis elegans

Por Glendinning, Susan K., Buckingham, Steven D., Sattelle, David B., Wonnacott, Susan, Wolstenholme, Adrian J.
Publicado em 2011

Development of an in vitro bioassay for measuring susceptibility to macrocyclic lactone anthelmintics in Dirofilaria immitis()

Por Evans, Christopher C., Moorhead, Andrew R., Storey, Bobby E., Wolstenholme, Adrian J., Kaplan, Ray M.
Publicado em 2013

Expression of nicotinic acetylcholine receptor subunits from parasitic nematodes in Caenorhabditis elegans

Por Sloan, Megan A., Reaves, Barbara J., Maclean, Mary J., Storey, Bob E., Wolstenholme, Adrian J.
Publicado no Mol Biochem Parasitol (2015)

How do the macrocyclic lactones kill filarial nematode larvae?

Por Wolstenholme, Adrian J., Maclean, Mary J., Coates, Ruby, McCoy, Ciaran J., Reaves, Barbara J.
Publicado no Invert Neurosci (2016)

Human Leukocytes Kill Brugia malayi Microfilariae Independently of DNA-Based Extracellular Trap Release

Por McCoy, Ciaran J., Reaves, Barbara J., Giguère, Steeve, Coates, Ruby, Rada, Balázs, Wolstenholme, Adrian J.
Publicado no PLoS Negl Trop Dis (2017)

Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels

Por Lynagh, Timothy, Beech, Robin N., Lalande, Maryline J., Keller, Kevin, Cromer, Brett A., Wolstenholme, Adrian J., Laube, Bodo
Publicado no Sci Rep (2015)

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes

Por Bennett, Hayley M, Lees, Kristin, Harper, Kate M, Jones, Andrew K, Sattelle, David B, Wonnacott, Susan, Wolstenholme, Adrian J
Publicado em 2012

The Nicotinic Acetylcholine Receptors of the Parasitic Nematode Ascaris suum: Formation of Two Distinct Drug Targets by Varying the Relative Expression Levels of Two Subunits

Por Williamson, Sally M., Robertson, Alan P., Brown, Laurence, Williams, Tracey, Woods, Debra J., Martin, Richard J., Sattelle, David B., Wolstenholme, Adrian J.
Publicado em 2009

Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes

Por Courtot, Elise, Charvet, Claude L., Beech, Robin N., Harmache, Abdallah, Wolstenholme, Adrian J., Holden-Dye, Lindy, O’Connor, Vincent, Peineau, Nicolas, Woods, Debra J., Neveu, Cedric
Publicado no PLoS Pathog (2015)

Characterization of the Ca(2+)-Gated and Voltage-Dependent K(+)-Channel Slo-1 of Nematodes and Its Interaction with Emodepside

Por Kulke, Daniel, von Samson-Himmelstjerna, Georg, Miltsch, Sandra M., Wolstenholme, Adrian J., Jex, Aaron R., Gasser, Robin B., Ballesteros, Cristina, Geary, Timothy G., Keiser, Jennifer, Townson, Simon, Harder, Achim, Krücken, Jürgen
Publicado no PLoS Negl Trop Dis (2014)

Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug/receptor interactions

Por Kotze, Andrew C., Hunt, Peter W., Skuce, Philip, von Samson-Himmelstjerna, Georg, Martin, Richard J., Sager, Heinz, Krücken, Jürgen, Hodgkinson, Jane, Lespine, Anne, Jex, Aaron R., Gilleard, John S., Beech, Robin N., Wolstenholme, Adrian J., Demeler, Janina, Robertson, Alan P., Charvet, Claude L., Neveu, Cedric, Kaminsky, Ronald, Rufener, Lucien, Alberich, Melanie, Menez, Cecile, Prichard, Roger K.
Publicado no Int J Parasitol Drugs Drug Resist (2014)