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How do the macrocyclic lactones kill filarial nematode larvae?

The macrocyclic lactones (MLs) are one of the few classes of drug used in the control of the human filarial infections, onchocerciasis and lymphatic filariasis, and the only one used to prevent heartworm disease in dogs and cats. Despite their importance in preventing filarial diseases, the way in w...

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Detalhes bibliográficos
Publicado no:Invert Neurosci
Main Authors: Wolstenholme, Adrian J., Maclean, Mary J., Coates, Ruby, McCoy, Ciaran J., Reaves, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472989/
https://ncbi.nlm.nih.gov/pubmed/27279086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10158-016-0190-7
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