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How do the macrocyclic lactones kill filarial nematode larvae?

The macrocyclic lactones (MLs) are one of the few classes of drug used in the control of the human filarial infections, onchocerciasis and lymphatic filariasis, and the only one used to prevent heartworm disease in dogs and cats. Despite their importance in preventing filarial diseases, the way in w...

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Bibliografske podrobnosti
izdano v:Invert Neurosci
Main Authors: Wolstenholme, Adrian J., Maclean, Mary J., Coates, Ruby, McCoy, Ciaran J., Reaves, Barbara J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472989/
https://ncbi.nlm.nih.gov/pubmed/27279086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10158-016-0190-7
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