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Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels

Glutamate is an indispensable neurotransmitter, triggering postsynaptic signals upon recognition by postsynaptic receptors. We questioned the phylogenetic position and the molecular details of when and where glutamate recognition arose in the glutamate-gated chloride channels. Experiments revealed t...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Lynagh, Timothy, Beech, Robin N., Lalande, Maryline J., Keller, Kevin, Cromer, Brett A., Wolstenholme, Adrian J., Laube, Bodo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338433/
https://ncbi.nlm.nih.gov/pubmed/25708000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08558
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