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Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels

Glutamate is an indispensable neurotransmitter, triggering postsynaptic signals upon recognition by postsynaptic receptors. We questioned the phylogenetic position and the molecular details of when and where glutamate recognition arose in the glutamate-gated chloride channels. Experiments revealed t...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Lynagh, Timothy, Beech, Robin N., Lalande, Maryline J., Keller, Kevin, Cromer, Brett A., Wolstenholme, Adrian J., Laube, Bodo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338433/
https://ncbi.nlm.nih.gov/pubmed/25708000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08558
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