The Nicotinic Acetylcholine Receptors of the Parasitic Nematode Ascaris suum: Formation of Two Distinct Drug Targets by Varying the Relative Expression Levels of Two Subunits

Parasitic nematodes are of medical and veterinary importance, adversely affecting human health and animal welfare. Ascaris suum is a gastrointestinal parasite of pigs; in addition to its veterinary significance it is a good model of the human parasite Ascaris lumbricoides, estimated to infect ∼1.4 b...

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Bibliographic Details
Main Authors: Williamson, Sally M., Robertson, Alan P., Brown, Laurence, Williams, Tracey, Woods, Debra J., Martin, Richard J., Sattelle, David B., Wolstenholme, Adrian J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705655/
https://ncbi.nlm.nih.gov/pubmed/19609360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000517
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