Pharmacological profile of Ascaris suum ACR‐16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues

BACKGROUND AND PURPOSE: Control of nematode parasite infections relies largely on anthelmintic drugs, several of which act on nicotinic ACh receptors (nAChRs), and there are concerns about the development of resistance. There is an urgent need for development of new compounds to overcome resistance...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Abongwa, Melanie, Buxton, Samuel K, Courtot, Elise, Charvet, Claude L, Neveu, Cédric, McCoy, Ciaran J, Verma, Saurabh, Robertson, Alan P, Martin, Richard J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959957/
https://ncbi.nlm.nih.gov/pubmed/27238203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13524
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