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Characterization of the Ca(2+)-Gated and Voltage-Dependent K(+)-Channel Slo-1 of Nematodes and Its Interaction with Emodepside
The cyclooctadepsipeptide emodepside and its parent compound PF1022A are broad-spectrum nematicidal drugs which are able to eliminate nematodes resistant to other anthelmintics. The mode of action of cyclooctadepsipeptides is only partially understood, but involves the latrophilin Lat-1 receptor and...
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| Publicado no: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270693/ https://ncbi.nlm.nih.gov/pubmed/25521608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003401 |
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