Development of emodepside as a possible adulticidal treatment for human onchocerciasis—The fruit of a successful industrial–academic collaboration

Current mass drug administration (MDA) programs for the treatment of human river blindness (onchocerciasis) caused by the filarial worm Onchocerca volvulus rely on ivermectin, an anthelmintic originally developed for animal health. These treatments are primarily directed against migrating microfilar...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Krücken, Jürgen, Holden-Dye, Lindy, Keiser, Jennifer, Prichard, Roger K., Townson, Simon, Makepeace, Benjamin L., Hübner, Marc P., Hahnel, Steffen R., Scandale, Ivan, Harder, Achim, Kulke, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297762/
https://ncbi.nlm.nih.gov/pubmed/34293063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009682
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