Emodepside targets SLO-1 channels of Onchocerca ochengi and induces broad anthelmintic effects in a bovine model of onchocerciasis

Onchocerciasis (river blindness), caused by the filarial worm Onchocerca volvulus, is a neglected tropical disease mostly affecting sub-Saharan Africa and is responsible for >1.3 million years lived with disability. Current control relies almost entirely on ivermectin, which suppresses symptoms c...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Bah, Germanus S., Schneckener, Sebastian, Hahnel, Steffen R., Bayang, Nicolas H., Fieseler, Helena, Schmuck, Gabriele M., Krebber, Ralph, Sarr, Anouk, Terjung, Carsten, Ngangyung, Henrietta F., Ekale, David D., Mfopit, Youssouf M., Rufener, Lucien, Graham-Brown, John, Tanya, Vincent N., Glenschek-Sieberth, Martin, Kulke, Daniel, Makepeace, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8202924/
https://ncbi.nlm.nih.gov/pubmed/34077488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009601
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