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Efficacy of Three-Week Oxytetracycline or Rifampin Monotherapy Compared with a Combination Regimen against the Filarial Nematode Onchocerca ochengi

Onchocerciasis (river blindness), caused by the filarial nematode Onchocerca volvulus, is a major cause of visual impairment and dermatitis in sub-Saharan Africa. As O. volvulus contains an obligatory bacterial symbiont (Wolbachia), it is susceptible to antibiotic chemotherapy, although current regi...

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Bibliografiske detaljer
Main Authors: Bah, Germanus S., Ward, Emma L., Srivastava, Abhishek, Trees, Alexander J., Tanya, Vincent N., Makepeace, Benjamin L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910861/
https://ncbi.nlm.nih.gov/pubmed/24247133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01995-13
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