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Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship.

Filarial nematodes are important and widespread parasites of animals and humans. We have been using the African bovine parasite Onchocerca ochengi as a chemotherapeutic model for O. volvulus, the causal organism of 'river blindness' in humans, for which there is no safe and effective drug...

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Autors principals: Langworthy, N G, Renz, A, Mackenstedt, U, Henkle-Dührsen, K, de Bronsvoort, M B, Tanya, V N, Donnelly, M J, Trees, A J
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1690645/
https://ncbi.nlm.nih.gov/pubmed/10885510
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