Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA(4) Hydrolase

door Hiesinger, Kerstin, Schott, Annika, Kramer, Jan S., Blöcher, René, Witt, Finja, Wittmann, Sandra K., Steinhilber, Dieter, Pogoryelov, Denys, Gerstmeier, Jana, Werz, Oliver, Proschak, Ewgenij
Gepubliceerd in ACS Med Chem Lett (2019)

Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase

door Meirer, Karin, Glatzel, Daniel, Kretschmer, Simon, Wittmann, Sandra K., Hartmann, Markus, Blöcher, René, Angioni, Carlo, Geisslinger, Gerd, Steinhilber, Dieter, Hofmann, Bettina, Fürst, Robert, Proschak, Ewgenij
Gepubliceerd in Molecules (2016)

PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation

door Kolodziej, Stephan, Kuvardina, Olga N., Oellerich, Thomas, Herglotz, Julia, Backert, Ingo, Kohrs, Nicole, Buscató, Estel.la, Wittmann, Sandra K., Salinas-Riester, Gabriela, Bonig, Halvard, Karas, Michael, Serve, Hubert, Proschak, Ewgenij, Lausen, Jörn
Gepubliceerd in 2014

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

door Garscha, Ulrike, Romp, Erik, Pace, Simona, Rossi, Antonietta, Temml, Veronika, Schuster, Daniela, König, Stefanie, Gerstmeier, Jana, Liening, Stefanie, Werner, Markus, Atze, Heiner, Wittmann, Sandra, Weinigel, Christina, Rummler, Silke, Scriba, Gerhard K., Sautebin, Lidia, Werz, Oliver
Gepubliceerd in Sci Rep (2017)

Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

door Göbel, Tamara, Diehl, Olaf, Heering, Jan, Merk, Daniel, Angioni, Carlo, Wittmann, Sandra K., Buscato, Estel.la, Kottke, Ramona, Weizel, Lilia, Schader, Tim, Maier, Thorsten J., Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Proschak, Ewgenij, Kahnt, Astrid S.
Gepubliceerd in Front Pharmacol (2019)

Computer-Aided Selective Optimization of Side Activities of Talinolol

door Hiesinger, Kerstin, Kramer, Jan S., Achenbach, Janosch, Moser, Daniel, Weber, Julia, Wittmann, Sandra K., Morisseau, Christophe, Angioni, Carlo, Geisslinger, Gerd, Kahnt, Astrid S., Kaiser, Astrid, Proschak, Anna, Steinhilber, Dieter, Pogoryelov, Denys, Wagner, Karen, Hammock, Bruce D., Proschak, Ewgenij
Gepubliceerd in ACS Med Chem Lett (2019)

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

door Kramer, Jan S., Woltersdorf, Stefano, Duflot, Thomas, Hiesinger, Kerstin, Lillich, Felix F., Knöll, Felix, Wittmann, Sandra K., Klingler, Franca-M., Brunst, Steffen, Chaikuad, Apirat, Morisseau, Christophe, Hammock, Bruce D., Buccellati, Carola, Sala, Angelo, Rovati, G. Enrico, Leuillier, Matthieu, Fraineau, Sylvain, Rondeaux, Julie, Hernandez-Olmos, Victor, Heering, Jan, Merk, Daniel, Pogoryelov, Denys, Steinhilber, Dieter, Knapp, Stefan, Bellien, Jeremy, Proschak, Ewgenij
Gepubliceerd in J Med Chem (2019)