Design of Dual Inhibitors of Soluble Epoxide Hydrolase and LTA(4) Hydrolase

Por Hiesinger, Kerstin, Schott, Annika, Kramer, Jan S., Blöcher, René, Witt, Finja, Wittmann, Sandra K., Steinhilber, Dieter, Pogoryelov, Denys, Gerstmeier, Jana, Werz, Oliver, Proschak, Ewgenij
Publicado no ACS Med Chem Lett (2019)

Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase

Por Meirer, Karin, Glatzel, Daniel, Kretschmer, Simon, Wittmann, Sandra K., Hartmann, Markus, Blöcher, René, Angioni, Carlo, Geisslinger, Gerd, Steinhilber, Dieter, Hofmann, Bettina, Fürst, Robert, Proschak, Ewgenij
Publicado no Molecules (2016)

PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation

Por Kolodziej, Stephan, Kuvardina, Olga N., Oellerich, Thomas, Herglotz, Julia, Backert, Ingo, Kohrs, Nicole, Buscató, Estel.la, Wittmann, Sandra K., Salinas-Riester, Gabriela, Bonig, Halvard, Karas, Michael, Serve, Hubert, Proschak, Ewgenij, Lausen, Jörn
Publicado em 2014

Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase

Por Garscha, Ulrike, Romp, Erik, Pace, Simona, Rossi, Antonietta, Temml, Veronika, Schuster, Daniela, König, Stefanie, Gerstmeier, Jana, Liening, Stefanie, Werner, Markus, Atze, Heiner, Wittmann, Sandra, Weinigel, Christina, Rummler, Silke, Scriba, Gerhard K., Sautebin, Lidia, Werz, Oliver
Publicado no Sci Rep (2017)

Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ

Por Göbel, Tamara, Diehl, Olaf, Heering, Jan, Merk, Daniel, Angioni, Carlo, Wittmann, Sandra K., Buscato, Estel.la, Kottke, Ramona, Weizel, Lilia, Schader, Tim, Maier, Thorsten J., Geisslinger, Gerd, Schubert-Zsilavecz, Manfred, Steinhilber, Dieter, Proschak, Ewgenij, Kahnt, Astrid S.
Publicado no Front Pharmacol (2019)

Computer-Aided Selective Optimization of Side Activities of Talinolol

Por Hiesinger, Kerstin, Kramer, Jan S., Achenbach, Janosch, Moser, Daniel, Weber, Julia, Wittmann, Sandra K., Morisseau, Christophe, Angioni, Carlo, Geisslinger, Gerd, Kahnt, Astrid S., Kaiser, Astrid, Proschak, Anna, Steinhilber, Dieter, Pogoryelov, Denys, Wagner, Karen, Hammock, Bruce D., Proschak, Ewgenij
Publicado no ACS Med Chem Lett (2019)

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

Por Kramer, Jan S., Woltersdorf, Stefano, Duflot, Thomas, Hiesinger, Kerstin, Lillich, Felix F., Knöll, Felix, Wittmann, Sandra K., Klingler, Franca-M., Brunst, Steffen, Chaikuad, Apirat, Morisseau, Christophe, Hammock, Bruce D., Buccellati, Carola, Sala, Angelo, Rovati, G. Enrico, Leuillier, Matthieu, Fraineau, Sylvain, Rondeaux, Julie, Hernandez-Olmos, Victor, Heering, Jan, Merk, Daniel, Pogoryelov, Denys, Steinhilber, Dieter, Knapp, Stefan, Bellien, Jeremy, Proschak, Ewgenij
Publicado no J Med Chem (2019)