Genetic modifiers of cancer risk in Lynch syndrome: a review

Por Talseth-Palmer, Bente A., Wijnen, Juul T., Grice, Desma M., Scott, Rodney J.
Publicado em 2013

8q23.3 and 11q23.1 as modifying loci influencing the risk for CRC in Lynch syndrome

Por Talseth-Palmer, Bente A, Scott, Rodney J, Vasen, Hans F A, Wijnen, Juul T
Publicado em 2012

The Risk of Extra-colonic, Extra-endometrial Cancer in the Lynch Syndrome

Por Watson, Patrice, Vasen, Hans F.A., Mecklin, Jukka-Pekka, Bernstein, Inge, Aarnio, Markku, Järvinen, Heikki J., Myrhøj, Torben, Sunde, Lone, Wijnen, Juul T., Lynch, Henry T.
Publicado em 2008

Splicing analysis for exonic and intronic mismatch repair gene variants associated with Lynch syndrome confirms high concordance between minigene assays and patient RNA analyses

Por van der Klift, Heleen M, Jansen, Anne M L, van der Steenstraten, Niki, Bik, Elsa C, Tops, Carli M J, Devilee, Peter, Wijnen, Juul T
Publicado no Mol Genet Genomic Med (2015)

Conventional and Tissue Microarray Immunohistochemical Expression Analysis of Mismatch Repair in Hereditary Colorectal Tumors

Por Hendriks, Yvonne, Franken, Patrick, Dierssen, Jan Willem, de Leeuw, Wiljo, Wijnen, Juul, Dreef, Enno, Tops, Carli, Breuning, Martijn, Bröcker-Vriends, Annette, Vasen, Hans, Fodde, Riccardo, Morreau, Hans
Publicado em 2003

Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome

Por Bellido, Fernando, Guinó, Elisabet, Jagmohan-Changur, Shantie, Seguí, Nuria, Pineda, Marta, Navarro, Matilde, Lázaro, Conxi, Blanco, Ignacio, Vasen, Hans FA, Moreno, Victor, Capellá, Gabriel, Wijnen, Juul T, Valle, Laura
Publicado em 2013

Exome Sequencing of Germline DNA from Non-BRCA1/2 Familial Breast Cancer Cases Selected on the Basis of aCGH Tumor Profiling

Por Hilbers, Florentine S., Meijers, Caro M., Laros, Jeroen F. J., van Galen, Michiel, Hoogerbrugge, Nicoline, Vasen, Hans F. A., Nederlof, Petra M., Wijnen, Juul T., van Asperen, Christi J., Devilee, Peter
Publicado em 2013

A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

Por Middeldorp, Anneke, Jagmohan-Changur, Shantie, Helmer, Quinta, van der Klift, Heleen M, Tops, Carli MJ, Vasen, Hans FA, Devilee, Peter, Morreau, Hans, Houwing-Duistermaat, Jeanine J, Wijnen, Juul T, van Wezel, Tom
Publicado em 2007

The importance of a large sample cohort for studies on modifier genes influencing disease severity in FAP patients

Por Talseth-Palmer, Bente A, Wijnen, Juul T, Andreassen, Eva K, Barker, Daniel, Jagmohan-Changur, Shantie, Tops, Carli M, Meldrum, Cliff, Spigelman, Allan, Hes, Frederik J, Van Wezel, Tom, Vasen, Hans FA, Scott, Rodney J
Publicado em 2013

Combined mismatch repair and POLE/POLD1 defects explain unresolved suspected Lynch syndrome cancers

Por Jansen, Anne ML, van Wezel, Tom, van den Akker, Brendy EWM, Ventayol Garcia, Marina, Ruano, Dina, Tops, Carli MJ, Wagner, Anja, Letteboer, Tom GW, Gómez-García, Encarna B, Devilee, Peter, Wijnen, Juul T, Hes, Frederik J, Morreau, Hans
Publicado no Eur J Hum Genet (2016)

Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ

Por Pahl, Jens HW, Kwappenberg, Kitty MC, Varypataki, Eleni M, Santos, Susy J, Kuijjer, Marieke L, Mohamed, Susan, Wijnen, Juul T, van Tol, Maarten JD, Cleton-Jansen, Anne-Marie, Egeler, R Maarten, Jiskoot, Wim, Lankester, Arjan C, Schilham, Marco W
Publicado em 2014

Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer

Por Elsayed, Fadwa A, Kets, C Marleen, Ruano, Dina, van den Akker, Brendy, Mensenkamp, Arjen R, Schrumpf, Melanie, Nielsen, Maartje, Wijnen, Juul T, Tops, Carli M, Ligtenberg, Marjolijn J, Vasen, Hans FA, Hes, Frederik J, Morreau, Hans, van Wezel, Tom
Publicado no Eur J Hum Genet (2015)

MUTYH gene variants and breast cancer in a Dutch case–control study

Por Out, Astrid A., Wasielewski, Marijke, Huijts, Petra E. A., van Minderhout, Ivonne J. H. M., Houwing-Duistermaat, Jeanine J., Tops, Carli M. J., Nielsen, Maartje, Seynaeve, Caroline, Wijnen, Juul T., Breuning, Martijn H., van Asperen, Christi J., Schutte, Mieke, Hes, Frederik J., Devilee, Peter
Publicado em 2012

Cancer occurrence during follow-up of the CAPP2 study -aspirin use for up to four years significantly reduces Lynch syndrome cancers for up to several years after completion of the...

Por Burn, John, Mathers, John C, Gerdes, Anne-Marie, Bisgaard, MarieLuise, Evans, Gareth, Eccles, Diana, Lindblom, Annika, Macrae, Findlay, Maher, Eamonn R, Mecklin, Jukka-Pekka, Moslein, Gabriela, Olschwang, Sylviane, Ramesar, Raj, Vasen, Hans FA, Wijnen, Juul, Barker, Gail, Elliott, Faye, Lynch, Henry, Bishop, D Tim
Publicado em 2010

Hereditary cancer registries improve the care of patients with a genetic predisposition to cancer: contributions from the Dutch Lynch syndrome registry

Por Vasen, Hans F. A., Velthuizen, Mary E., Kleibeuker, Jan H., Menko, Fred H., Nagengast, Fokke M., Cats, Annemieke, van der Meulen-de Jong, Andrea E., Breuning, Martijn H., Roukema, Anne J., van Leeuwen-Cornelisse, Inge, de Vos tot Nederveen Cappel, Wouter H., Wijnen, Juul T.
Publicado no Fam Cancer (2016)

Chromosome 8q23.3, 10p14 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome – a combined analysis of the Australian, Dutch and Polish Lynch syndrome cohorts

Por Talseth-Palmer, Bente A, Wijnen, Juul T, Brenne, Ingvild S, Jagmohan-Changur, Shantie, Ashton, Katie A, Tops, Carli M, Evans, Tiffany-Jane, McPhillips, Mary, Groombridge, Claire, Suchy, Janina, Kurzawski, Grzegorz, Spigelman, Allan, Møller, Pål, Morreau, Hans M, Van Wezel, Tom, Lubinski, Jan, Vasen, Hans FA, Scott, Rodney J
Publicado em 2012

Seven New Mutations in hMSH2, an HNPCC Gene, Identified by Denaturing Gradient-Gel Electrophoresis

Por Wijnen, Juul, Vasen, Hans, Khan, P. Meera, Menko, Fred H., van der Klift, Heleen, van Leeuwen, Claus, van den Broek, Marianne, van Leeuwen-Cornelisse, Inge, Nagengast, Fokko, Meijers-Heijboer, Anne, Lindhout, Dick, Griffioen, Gerrit, Cats, Annemieke, Kleibeuker, Jan, Varesco, Liliana, Bertario, Lucio, Bisgaard, Marie Luise, Mohr, Jan, Fodde, Riccardo
Publicado em 1995

CHEK2*1100delC homozygosity in the Netherlands—prevalence and risk of breast and lung cancer

Por Huijts, Petra EA, Hollestelle, Antoinette, Balliu, Brunilda, Houwing-Duistermaat, Jeanine J, Meijers, Caro M, Blom, Jannet C, Ozturk, Bahar, Krol-Warmerdam, Elly MM, Wijnen, Juul, Berns, Els MJJ, Martens, John WM, Seynaeve, Caroline, Kiemeney, Lambertus A, van der Heijden, Henricus F, Tollenaar, Rob AEM, Devilee, Peter, van Asperen, Christi J
Publicado em 2014

Colorectal cancer risk variants on 11q23 and 15q13 are associated with unexplained adenomatous polyposis

Por Hes, Frederik J, Ruano, Dina, Nieuwenhuis, Marry, Tops, Carli M, Schrumpf, Melanie, Nielsen, Maartje, Huijts, Petra E A, Wijnen, Juul T, Wagner, Anja, Gómez García, Encarna B, Sijmons, Rolf H, Menko, Fred H, Letteboer, Tom G W, Hoogerbrugge, Nicoline, Harryvan, Jan, Kampman, Ellen, Morreau, Hans, Vasen, Hans F A, van Wezel, Tom
Publicado em 2013

The CHEK2 1100delC Mutation Identifies Families with a Hereditary Breast and Colorectal Cancer Phenotype

Por Meijers-Heijboer, Hanne, Wijnen, Juul, Vasen, Hans, Wasielewski, Marijke, Wagner, Anja, Hollestelle, Antoinette, Elstrodt, Fons, van den Bos, Renate, de Snoo, Anja, Tjon A Fat, Grace, Brekelmans, Cecile, Jagmohan, Shantie, Franken, Patrick, Verkuijlen, Paul, van den Ouweland, Ans, Chapman, Pamela, Tops, Carli, Möslein, Gabriela, Burn, John, Lynch, Henry, Klijn, Jan, Fodde, Riccardo, Schutte, Mieke
Publicado em 2003