A procedure for the detection of linkage with high density SNP arrays in a large pedigree with colorectal cancer

BACKGROUND: The apparent dominant model of colorectal cancer (CRC) inheritance in several large families, without mutations in known CRC susceptibility genes, suggests the presence of so far unidentified genes with strong or moderate effect on the development of CRC. Linkage analysis could lead to i...

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Detalhes bibliográficos
Main Authors: Middeldorp, Anneke, Jagmohan-Changur, Shantie, Helmer, Quinta, van der Klift, Heleen M, Tops, Carli MJ, Vasen, Hans FA, Devilee, Peter, Morreau, Hans, Houwing-Duistermaat, Jeanine J, Wijnen, Juul T, van Wezel, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1784097/
https://ncbi.nlm.nih.gov/pubmed/17222328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-6
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