Clustering of known low and moderate risk alleles rather than a novel recessive high‐risk gene in non‐BRCA1/2 sib trios affected with breast cancer

door Hilbers, Florentine S., van ‘t Hof, Peter J., Meijers, Caro M., Mei, Hailiang, Michailidou, Kyriaki, Dennis, Joe, Hogervorst, Frans B. L., Nederlof, Petra M., van Asperen, Christi J., Devilee, Peter
Gepubliceerd in Int J Cancer (2020)

Exome Sequencing of Germline DNA from Non-BRCA1/2 Familial Breast Cancer Cases Selected on the Basis of aCGH Tumor Profiling

door Hilbers, Florentine S., Meijers, Caro M., Laros, Jeroen F. J., van Galen, Michiel, Hoogerbrugge, Nicoline, Vasen, Hans F. A., Nederlof, Petra M., Wijnen, Juul T., van Asperen, Christi J., Devilee, Peter
Gepubliceerd in 2013

An RB-1 loss of function gene signature as a tool to predict response to neoadjuvant chemotherapy plus anti-HER2 agents: a substudy of the NeoALTTO trial (BIG 1-06)

door Risi, Emanuela, Biagioni, Chiara, Benelli, Matteo, Migliaccio, Ilenia, McCartney, Amelia, Bonechi, Martina, Guarducci, Cristina, Hilbers, Florentine, Di Cosimo, Serena, Huober, Jens, Romagnoli, Dario, Boccalini, Giulia, Vitale, Stefania, Sotiriou, Christos, Biganzoli, Laura, Di Leo, Angelo, Malorni, Luca
Gepubliceerd in Ther Adv Med Oncol (2019)

Long-term cardiac outcomes of patients with HER2-positive breast cancer treated in the adjuvant lapatinib and/or trastuzumab Treatment Optimization Trial

door Eiger, Daniel, Pondé, Noam F., Agbor-Tarh, Dominique, Moreno-Aspitia, Alvaro, Piccart, Martine, Hilbers, Florentine S., Werner, Olena, Chumsri, Saranya, Dueck, Amylou, Kroep, Judith R., Gomez, Henry, Láng, István, Rodeheffer, Richard J., Ewer, Michael S., Suter, Thomas, de Azambuja, Evandro
Gepubliceerd in Br J Cancer (2020)

Prognostic role of distant disease-free interval from completion of adjuvant trastuzumab in HER2-positive early breast cancer: analysis from the ALTTO (BIG 2-06) trial

door Lambertini, Matteo, Agbor-Tarh, Dominique, Metzger-Filho, Otto, Ponde, Noam F, Poggio, Francesca, Hilbers, Florentine S, Korde, Larissa A, Chumsri, Saranya, Werner, Olena, Del Mastro, Lucia, Caparica, Rafael, Moebus, Volker, Moreno-Aspitia, Alvaro, Piccart, Martine J, de Azambuja, Evandro
Gepubliceerd in ESMO Open (2020)

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy

door Di Cosimo, Serena, Appierto, Valentina, Pizzamiglio, Sara, Silvestri, Marco, Baselga, José, Piccart, Martine, Huober, Jens, Izquierdo, Miguel, de la Pena, Lorena, Hilbers, Florentine S., de Azambuja, Evandro, Untch, Michael, Pusztai, Lajos, Pritchard, Kathleen, Nuciforo, Paolo, Vincent-Salomon, Anne, Symmans, Fraser, Apolone, Giovanni, de Braud, Filippo G., Iorio, Marilena V., Verderio, Paolo, Daidone, Maria Grazia
Gepubliceerd in Int J Mol Sci (2020)

Standard Anthracycline Based Versus Docetaxel-Capecitabine in Early High Clinical and/or Genomic Risk Breast Cancer in the EORTC 10041/BIG 3-04 MINDACT Phase III Trial

door Delaloge, Suzette, Piccart, Martine, Rutgers, Emiel, Litière, Saskia, van ’t Veer, Laura J., van den Berkmortel, Franchette, Brain, Etienne, Dudek-Peric, Aleksandra, Gil-Gil, Miguel, Gomez, Patricia, Hilbers, Florentine S., Khalil, Zaman, Knox, Susan, Kuemmel, Sherko, Kunz, Georg, Lesur, Anne, Pierga, Jean-Yves, Ravdin, Peter, Rubio, Isabel T., Saghatchian, Mahasti, Smilde, Tineke J., Thompson, Alastair M., Viale, Giuseppe, Zoppoli, Gabriele, Vuylsteke, Peter, Tryfonidis, Konstantinos, Poncet, Coralie, Bogaerts, Jan, Cardoso, Fatima
Gepubliceerd in J Clin Oncol (2020)

Whole Exome Sequencing Suggests Much of Non-BRCA1/BRCA2 Familial Breast Cancer Is Due to Moderate and Low Penetrance Susceptibility Alleles

door Gracia-Aznarez, Francisco Javier, Fernandez, Victoria, Pita, Guillermo, Peterlongo, Paolo, Dominguez, Orlando, de la Hoya, Miguel, Duran, Mercedes, Osorio, Ana, Moreno, Leticia, Gonzalez-Neira, Anna, Rosa-Rosa, Juan Manuel, Sinilnikova, Olga, Mazoyer, Sylvie, Hopper, John, Lazaro, Conchi, Southey, Melissa, Odefrey, Fabrice, Manoukian, Siranoush, Catucci, Irene, Caldes, Trinidad, Lynch, Henry T., Hilbers, Florentine S. M., van Asperen, Christi J., Vasen, Hans F. A., Goldgar, David, Radice, Paolo, Devilee, Peter, Benitez, Javier
Gepubliceerd in 2013

Evaluation of multiple transcriptomic gene risk signatures in male breast cancer

door Bayani, Jane, Poncet, Coralie, Crozier, Cheryl, Neven, Anouk, Piper, Tammy, Cunningham, Carrie, Sobol, Monika, Aebi, Stefan, Benstead, Kim, Bogler, Oliver, Dal Lago, Lissandra, Fraser, Judith, Hilbers, Florentine, Hedenfalk, Ingrid, Korde, Larissa, Linderholm, Barbro, Martens, John, Middleton, Lavinia, Murray, Melissa, Kelly, Catherine, Nilsson, Cecilia, Nowaczyk, Monika, Peeters, Stephanie, Peric, Aleksandra, Porter, Peggy, Schröder, Carolien, Rubio, Isabel T., Ruddy, Kathryn J., van Asperen, Christi, Van Den Weyngaert, Danielle, van Deurzen, Carolien, van Leeuwen-Stok, Elise, Vermeij, Joanna, Winer, Eric, Giordano, Sharon H., Cardoso, Fatima, Bartlett, John M. S.
Gepubliceerd in NPJ Breast Cancer (2021)

COMPLEXO: identifying the missing heritability of breast cancer via next generation collaboration

door Southey, Melissa C, Park, Daniel J, Nguyen-Dumont, Tu, Campbell, Ian, Thompson, Ella, Trainer, Alison H, Chenevix-Trench, Georgia, Simard, Jacques, Dumont, Martine, Soucy, Penny, Thomassen, Mads, Jønson, Lars, Pedersen, Inge S, Hansen, Thomas VO, Nevanlinna, Heli, Khan, Sofia, Sinilnikova, Olga, Mazoyer, Sylvie, Lesueur, Fabienne, Damiola, Francesca, Schmutzler, Rita, Meindl, Alfons, Hahnen, Eric, Dufault, Michael R, Chris Chan, TL, Kwong, Ava, Barkardóttir, Rosa, Radice, Paolo, Peterlongo, Paolo, Devilee, Peter, Hilbers, Florentine, Benitez, Javier, Kvist, Anders, Törngren, Therese, Easton, Douglas, Hunter, David, Lindstrom, Sara, Kraft, Peter, Zheng, Wei, Gao, Yu-Tang, Long, Jirong, Ramus, Susan, Feng, Bing-Jian, Weitzel, Jeffrey N, Nathanson, Katherine, Offit, Kenneth, Joseph, Vijai, Robson, Mark, Schrader, Kasmintan, Wang, San Ming, Kim, Yeong C, Lynch, Henry, Snyder, Carrie, Tavtigian, Sean, Neuhausen, Susan, Couch, Fergus J, Goldgar, David E
Gepubliceerd in 2013

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor

door Peterlongo, Paolo, Catucci, Irene, Colombo, Mara, Caleca, Laura, Mucaki, Eliseos, Bogliolo, Massimo, Marin, Maria, Damiola, Francesca, Bernard, Loris, Pensotti, Valeria, Volorio, Sara, Dall'Olio, Valentina, Meindl, Alfons, Bartram, Claus, Sutter, Christian, Surowy, Harald, Sornin, Valérie, Dondon, Marie-Gabrielle, Eon-Marchais, Séverine, Stoppa-Lyonnet, Dominique, Andrieu, Nadine, Sinilnikova, Olga M., Mitchell, Gillian, James, Paul A., Thompson, Ella, Marchetti, Marina, Verzeroli, Cristina, Tartari, Carmen, Capone, Gabriele Lorenzo, Putignano, Anna Laura, Genuardi, Maurizio, Medici, Veronica, Marchi, Isabella, Federico, Massimo, Tognazzo, Silvia, Matricardi, Laura, Agata, Simona, Dolcetti, Riccardo, Puppa, Lara Della, Cini, Giulia, Gismondi, Viviana, Viassolo, Valeria, Perfumo, Chiara, Mencarelli, Maria Antonietta, Baldassarri, Margherita, Peissel, Bernard, Roversi, Gaia, Silvestri, Valentina, Rizzolo, Piera, Spina, Francesca, Vivanet, Caterina, Tibiletti, Maria Grazia, Caligo, Maria Adelaide, Gambino, Gaetana, Tommasi, Stefania, Pilato, Brunella, Tondini, Carlo, Corna, Chiara, Bonanni, Bernardo, Barile, Monica, Osorio, Ana, Benitez, Javier, Balestrino, Luisa, Ottini, Laura, Manoukian, Siranoush, Pierotti, Marco A., Renieri, Alessandra, Varesco, Liliana, Couch, Fergus J., Wang, Xianshu, Devilee, Peter, Hilbers, Florentine S., van Asperen, Christi J., Viel, Alessandra, Montagna, Marco, Cortesi, Laura, Diez, Orland, Balmaña, Judith, Hauke, Jan, Schmutzler, Rita K., Papi, Laura, Pujana, Miguel Angel, Lázaro, Conxi, Falanga, Anna, Offit, Kenneth, Vijai, Joseph, Campbell, Ian, Burwinkel, Barbara, Kvist, Anders, Ehrencrona, Hans, Mazoyer, Sylvie, Pizzamiglio, Sara, Verderio, Paolo, Surralles, Jordi, Rogan, Peter K., Radice, Paolo
Gepubliceerd in Hum Mol Genet (2015)