RNA processing and genome stability: cause and consequence

por Wickramasinghe, Vihandha O., Venkitaraman, Ashok R.
Publicado en Mol Cell (2016)

GANP enhances the efficiency of mRNA nuclear export in mammalian cells

por Wickramasinghe, Vihandha O, Stewart, Murray, Laskey, Ronald A
Publicado 2010

Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export

por Jani, Divyang, Lutz, Sheila, Hurt, Ed, Laskey, Ronald A., Stewart, Murray, Wickramasinghe, Vihandha O.
Publicado 2012

Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP

por Wickramasinghe, Vihandha O., Andrews, Robert, Ellis, Peter, Langford, Cordelia, Gurdon, John B., Stewart, Murray, Venkitaraman, Ashok R., Laskey, Ronald A.
Publicado 2014

Impact of Alternative Splicing on the Human Proteome

por Liu, Yansheng, Gonzàlez-Porta, Mar, Santos, Sergio, Brazma, Alvis, Marioni, John C., Aebersold, Ruedi, Venkitaraman, Ashok R., Wickramasinghe, Vihandha O.
Publicado en Cell Rep (2017)

MCM3AP Is Transcribed from a Promoter within an Intron of the Overlapping Gene for GANP

por Wickramasinghe, Vihandha O., McMurtrie, Paul I.A., Marr, Jackie, Amagase, Yoko, Main, Sarah, Mills, Anthony D., Laskey, Ronald A., Takei, Yoshinori
Publicado 2011

Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength

por Wickramasinghe, Vihandha O., Gonzàlez-Porta, Mar, Perera, David, Bartolozzi, Arthur R., Sibley, Christopher R., Hallegger, Martina, Ule, Jernej, Marioni, John C., Venkitaraman, Ashok R.
Publicado en Genome Biol (2015)

mRNA Export from Mammalian Cell Nuclei Is Dependent on GANP

por Wickramasinghe, Vihandha O., McMurtrie, Paul I.A., Mills, Anthony D., Takei, Yoshinori, Penrhyn-Lowe, Sue, Amagase, Yoko, Main, Sarah, Marr, Jackie, Stewart, Murray, Laskey, Ronald A.
Publicado 2010

Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice

por Chappaz, Stéphane, Law, Charity W., Dowling, Mark R., Carey, Kirstyn T., Lane, Rachael M., Ngo, Linh H., Wickramasinghe, Vihandha O., Smyth, Gordon K., Ritchie, Matthew E., Kile, Benjamin T.
Publicado en Blood Adv (2020)

A systems view of spliceosomal assembly and branchpoints with iCLIP

por Briese, Michael, Haberman, Nejc, Sibley, Christopher R., Faraway, Rupert, Elser, Andrea S., Chakrabarti, Anob M., Wang, Zhen, König, Julian, Perera, David, Wickramasinghe, Vihandha O., Venkitaraman, Ashok R., Luscombe, Nicholas M., Saieva, Luciano, Pellizzoni, Livio, Smith, Christopher W.J., Curk, Tomaž, Ule, Jernej
Publicado en Nat Struct Mol Biol (2019)

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

por Hogg, Simon J., Motorna, Olga, Cluse, Leonie A., Johanson, Timothy M., Coughlan, Hannah D., Raviram, Ramya, Myers, Robert M., Costacurta, Matteo, Todorovski, Izabela, Pijpers, Lizzy, Bjelosevic, Stefan, Williams, Tobias, Huskins, Shannon N., Kearney, Conor J., Devlin, Jennifer R., Fan, Zheng, Jabbari, Jafar S., Martin, Ben P., Fareh, Mohamed, Kelly, Madison J., Dupéré-Richer, Daphné, Sandow, Jarrod J., Feran, Breon, Knight, Deborah, Khong, Tiffany, Spencer, Andrew, Harrison, Simon J., Gregory, Gareth, Wickramasinghe, Vihandha O., Webb, Andrew I., Taberlay, Phillippa C., Bromberg, Kenneth D., Lai, Albert, Papenfuss, Anthony T., Smyth, Gordon K., Allan, Rhys S., Licht, Jonathan D., Landau, Dan A., Abdel-Wahab, Omar, Shortt, Jake, Vervoort, Stephin J., Johnstone, Ricky W.
Publicado en Mol Cell (2021)