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A systems view of spliceosomal assembly and branchpoints with iCLIP
Studies of spliceosomal interactions are challenging due to their dynamic nature. Here we employed spliceosome iCLIP, which immunoprecipitates SmB along with snRNPs and auxiliary RNA binding proteins (RBPs), to map spliceosome engagement with pre-mRNAs in human cell lines. This revealed seven peaks...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Struct Mol Biol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6859068/ https://ncbi.nlm.nih.gov/pubmed/31570875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0300-4 |
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