Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength

BACKGROUND: Sequential assembly of the human spliceosome on RNA transcripts regulates splicing across the human transcriptome. The core spliceosome component PRPF8 is essential for spliceosome assembly through its participation in ribonucleoprotein (RNP) complexes for splice-site recognition, branch...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Genome Biol
Glavni autori: Wickramasinghe, Vihandha O., Gonzàlez-Porta, Mar, Perera, David, Bartolozzi, Arthur R., Sibley, Christopher R., Hallegger, Martina, Ule, Jernej, Marioni, John C., Venkitaraman, Ashok R.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578845/
https://ncbi.nlm.nih.gov/pubmed/26392272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0749-3
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items