PTH/PTHrP Receptor Signaling, Allostery, and Structures

od Sutkeviciute, Ieva, Clark, Lisa J., White, Alex D., Gardella, Thomas J., Vilardaga, Jean-Pierre
Wydane w Trends Endocrinol Metab (2019)

Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis

od Naim, Nyla, White, Alex D., Reece, Jeff M., Wankhede, Mamta, Zhang, Xuefeng, Vilardaga, Jean-Pierre, Altschuler, Daniel L.
Wydane w J Biol Chem (2019)

Use of Backbone Modification to Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism

od Liu, Shi, Jean-Alphonse, Frederic G., White, Alex D., Wootten, Denise, Sexton, Patrick M., Gardella, Thomas J., Vilardaga, Jean-Pierre, Gellman, Samuel H.
Wydane w J Am Chem Soc (2019)

Ca(2+) allostery in PTH-receptor signaling

od White, Alex D., Fang, Fei, Jean-Alphonse, Frédéric G., Clark, Lisa J., An, Hyun-Jung, Liu, Hongda, Zhao, Yang, Reynolds, Shelley L., Lee, Sihoon, Xiao, Kunhong, Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
Wydane w Proc Natl Acad Sci U S A (2019)

G(q/11)-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR

od White, Alex D., Jean-Alphonse, Frederic G., Fang, Fei, Peña, Karina A., Liu, Shi, König, Gabriele M., Inoue, Asuka, Aslanoglou, Despoina, Gellman, Samuel H., Kostenis, Evi, Xiao, Kunhong, Vilardaga, Jean-Pierre
Wydane w Proc Natl Acad Sci U S A (2020)

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

od Clark, Lisa J., Krieger, James, White, Alex D., Bondarenko, Vasyl, Lei, Saifei, Fang, Fei, Lee, Ji Young, Doruker, Pemra, Böttke, Thore, Jean-Alphonse, Frederic, Tang, Pei, Gardella, Thomas J., Xiao, Kunhong, Sutkeviciute, Ieva, Coin, Irene, Bahar, Ivet, Vilardaga, Jean-Pierre
Wydane w Nat Chem Biol (2020)

PTH Hypersecretion Triggered by a GABA(B1) and Ca(2+)-sensing Receptor Heterocomplex in Hyperparathyroidism

od Chang, Wenhan, Tu, Chia-Ling, Jean-Alphonse, Frederic, Herberger, Amanda, Cheng, Zhiqiang, Hwong, Jenna, Ho, Hanson, Li, Alfred, Wang, Dawei, Liu, Hongda, White, Alex D., Suh, Insoo, Shen, Wen, Duh, Quan-Yang, Khanafshar, Elham, Shoback, Dolores M., Xiao, Kunhong, Vilardaga, Jean-Pierre
Wydane w Nat Metab (2020)

Structure and dynamics of the active human parathyroid hormone receptor-1

od Zhao, Li-Hua, Ma, Shanshan, Sutkeviciute, Ieva, Shen, Dan-Dan, Zhou, X. Edward, de Waal, Parker W., Li, Chen-Yao, Kang, Yanyong, Clark, Lisa J., Jean-Alphonse, Frederic G., White, Alex D., Yang, Dehua, Dai, Antao, Cai, Xiaoqing, Chen, Jian, Li, Cong, Jiang, Yi, Watanabe, Tomoyuki, Gardella, Thomas J., Melcher, Karsten, Wang, Ming-Wei, Vilardaga, Jean-Pierre, Xu, H. Eric, Zhang, Yan
Wydane w Science (2019)