PTH/PTHrP Receptor Signaling, Allostery, and Structures

著者: Sutkeviciute, Ieva, Clark, Lisa J., White, Alex D., Gardella, Thomas J., Vilardaga, Jean-Pierre
出版年 Trends Endocrinol Metab (2019)

Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis

著者: Naim, Nyla, White, Alex D., Reece, Jeff M., Wankhede, Mamta, Zhang, Xuefeng, Vilardaga, Jean-Pierre, Altschuler, Daniel L.
出版年 J Biol Chem (2019)

Use of Backbone Modification to Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism

著者: Liu, Shi, Jean-Alphonse, Frederic G., White, Alex D., Wootten, Denise, Sexton, Patrick M., Gardella, Thomas J., Vilardaga, Jean-Pierre, Gellman, Samuel H.
出版年 J Am Chem Soc (2019)

Ca(2+) allostery in PTH-receptor signaling

著者: White, Alex D., Fang, Fei, Jean-Alphonse, Frédéric G., Clark, Lisa J., An, Hyun-Jung, Liu, Hongda, Zhao, Yang, Reynolds, Shelley L., Lee, Sihoon, Xiao, Kunhong, Sutkeviciute, Ieva, Vilardaga, Jean-Pierre
出版年 Proc Natl Acad Sci U S A (2019)

G(q/11)-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR

著者: White, Alex D., Jean-Alphonse, Frederic G., Fang, Fei, Peña, Karina A., Liu, Shi, König, Gabriele M., Inoue, Asuka, Aslanoglou, Despoina, Gellman, Samuel H., Kostenis, Evi, Xiao, Kunhong, Vilardaga, Jean-Pierre
出版年 Proc Natl Acad Sci U S A (2020)

Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation

著者: Clark, Lisa J., Krieger, James, White, Alex D., Bondarenko, Vasyl, Lei, Saifei, Fang, Fei, Lee, Ji Young, Doruker, Pemra, Böttke, Thore, Jean-Alphonse, Frederic, Tang, Pei, Gardella, Thomas J., Xiao, Kunhong, Sutkeviciute, Ieva, Coin, Irene, Bahar, Ivet, Vilardaga, Jean-Pierre
出版年 Nat Chem Biol (2020)

PTH Hypersecretion Triggered by a GABA(B1) and Ca(2+)-sensing Receptor Heterocomplex in Hyperparathyroidism

著者: Chang, Wenhan, Tu, Chia-Ling, Jean-Alphonse, Frederic, Herberger, Amanda, Cheng, Zhiqiang, Hwong, Jenna, Ho, Hanson, Li, Alfred, Wang, Dawei, Liu, Hongda, White, Alex D., Suh, Insoo, Shen, Wen, Duh, Quan-Yang, Khanafshar, Elham, Shoback, Dolores M., Xiao, Kunhong, Vilardaga, Jean-Pierre
出版年 Nat Metab (2020)

Structure and dynamics of the active human parathyroid hormone receptor-1

著者: Zhao, Li-Hua, Ma, Shanshan, Sutkeviciute, Ieva, Shen, Dan-Dan, Zhou, X. Edward, de Waal, Parker W., Li, Chen-Yao, Kang, Yanyong, Clark, Lisa J., Jean-Alphonse, Frederic G., White, Alex D., Yang, Dehua, Dai, Antao, Cai, Xiaoqing, Chen, Jian, Li, Cong, Jiang, Yi, Watanabe, Tomoyuki, Gardella, Thomas J., Melcher, Karsten, Wang, Ming-Wei, Vilardaga, Jean-Pierre, Xu, H. Eric, Zhang, Yan
出版年 Science (2019)