Acute Myeloid Leukemia and the Bone Marrow Niche—Take a Closer Look

по Behrmann, Lena, Wellbrock, Jasmin, Fiedler, Walter
Опубликовано в: Front Oncol (2018)

Downregulation of GLI3 Expression Mediates Chemotherapy Resistance in Acute Myeloid Leukemia

по Freisleben, Fabian, Behrmann, Lena, Thaden, Vanessa, Muschhammer, Jana, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Опубликовано в: Int J Mol Sci (2020)

The bone microenvironment promotes tumor growth and tissue perfusion compared with striated muscle in a preclinical model of prostate cancer in vivo

по Mussawy, Haider, Viezens, Lennart, Schroeder, Malte, Hettenhausen, Svenja, Sündermann, Jördis, Wellbrock, Jasmin, Kossow, Kai, Schaefer, Christian
Опубликовано в: BMC Cancer (2018)

Mechanisms of Tumor-Lymphatic Interactions in Invasive Breast and Prostate Carcinoma

по Oliveira-Ferrer, Leticia, Milde-Langosch, Karin, Eylmann, Kathrin, Rossberg, Maila, Müller, Volkmar, Schmalfeldt, Barbara, Witzel, Isabell, Wellbrock, Jasmin, Fiedler, Walter
Опубликовано в: Int J Mol Sci (2020)

Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prol...

по Oliveira-Ferrer, Leticia, Wellbrock, Jasmin, Bartsch, Udo, Murga Penas, Eva Maria, Hauschild, Jessica, Klokow, Marianne, Bokemeyer, Carsten, Fiedler, Walter, Schuch, Gunter
Опубликовано 2013

Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia

по Latuske, Emily-Marie, Stamm, Hauke, Klokow, Marianne, Vohwinkel, Gabi, Muschhammer, Jana, Bokemeyer, Carsten, Jücker, Manfred, Kebenko, Maxim, Fiedler, Walter, Wellbrock, Jasmin
Опубликовано в: Oncotarget (2017)

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

по Velthaus, Arne, Cornils, Kerstin, Hennigs, Jan K., Grüb, Saskia, Stamm, Hauke, Wicklein, Daniel, Bokemeyer, Carsten, Heuser, Michael, Windhorst, Sabine, Fiedler, Walter, Wellbrock, Jasmin
Опубликовано в: Cancers (Basel) (2019)

Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer

по Stamm, Hauke, Oliveira-Ferrer, Leticia, Grossjohann, Eva-Maria, Muschhammer, Jana, Thaden, Vanessa, Brauneck, Franziska, Kischel, Roman, Müller, Volkmar, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Опубликовано в: Oncoimmunology (2019)

Strong fascin expression promotes metastasis independent of its F-actin bundling activity

по Heinz, Lisa S., Muhs, Stefanie, Schiewek, Johanna, Grüb, Saskia, Nalaskowski, Marcus, Lin, Yuan-Na, Wikman, Harriet, Oliveira-Ferrer, Leticia, Lange, Tobias, Wellbrock, Jasmin, Konietzny, Anja, Mikhaylova, Marina, Windhorst, Sabine
Опубликовано в: Oncotarget (2017)

High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells

по Teo Hansen Selnø, Anette, Schlichtner, Stephanie, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Berger, Steffen M., Klenova, Elena, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Опубликовано в: Front Immunol (2021)

Cortisol facilitates the immune escape of human acute myeloid leukemia cells by inducing latrophilin 1 expression

по Sakhnevych, Svetlana S., Yasinska, Inna M., Bratt, Alison M., Benlaouer, Ouafa, Gonçalves Silva, Isabel, Hussain, Rohanah, Siligardi, Giuliano, Fiedler, Walter, Wellbrock, Jasmin, Gibbs, Bernhard F., Ushkaryov, Yuri A., Sumbayev, Vadim V.
Опубликовано в: Cell Mol Immunol (2018)

High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression

по Yasinska, Inna M., Gonçalves Silva, Isabel, Sakhnevych, Svetlana S., Ruegg, Laura, Hussain, Rohanah, Siligardi, Giuliano, Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Raap, Ulrike, Berger, Steffen, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Опубликовано в: Oncoimmunology (2018)

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer

по Lange, Tobias, Oh-Hohenhorst, Su Jung, Joosse, Simon A., Pantel, Klaus, Hahn, Oliver, Gosau, Tobias, Dyshlovoy, Sergey A., Wellbrock, Jasmin, Feldhaus, Susanne, Maar, Hanna, Gehrcke, Renate, Kluth, Martina, Simon, Ronald, Schlomm, Thorsten, Huland, Hartwig, Schumacher, Udo
Опубликовано в: Sci Rep (2018)

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

по Gonçalves Silva, Isabel, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Hussain, Rohanah, Siligardi, Giuliano, Ceccone, Giacomo, Berger, Steffen M., Ushkaryov, Yuri A., Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Опубликовано в: EBioMedicine (2017)

Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 express...

по Selnø, Anette Teo Hansen, Schlichtner, Stephanie, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Klenova, Elena, Pavlova, Ludmila, Gibbs, Bernhard F., Degen, Martin, Schnyder, Isabelle, Aliu, Nijas, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Опубликовано в: Aging (Albany NY) (2020)

Overexpression of Gremlin-1 in Patients with Loeys-Dietz Syndrome: Implications on Pathophysiology and Early Disease Detection

по Wellbrock, Jasmin, Sheikhzadeh, Sara, Oliveira-Ferrer, Leticia, Stamm, Hauke, Hillebrand, Mathias, Keyser, Britta, Klokow, Marianne, Vohwinkel, Gabi, Bonk, Veronika, Otto, Benjamin, Streichert, Thomas, Balabanov, Stefan, Hagel, Christian, Rybczynski, Meike, Bentzien, Frank, Bokemeyer, Carsten, von Kodolitsch, Yskert, Fiedler, Walter
Опубликовано 2014

Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity

по Yasinska, Inna M., Meyer, N. Helge, Schlichtner, Stephanie, Hussain, Rohanah, Siligardi, Giuliano, Casely-Hayford, Maxwell, Fiedler, Walter, Wellbrock, Jasmin, Desmet, Cloe, Calzolai, Luigi, Varani, Luca, Berger, Steffen M., Raap, Ulrike, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Опубликовано в: Front Immunol (2020)

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option

по Stamm, Hauke, Klingler, Felix, Grossjohann, Eva-Maria, Muschhammer, Jana, Vettorazzi, Eik, Heuser, Michael, Mock, Ulrike, Thol, Felicitas, Vohwinkel, Gabi, Latuske, Emily, Bokemeyer, Carsten, Kischel, Roman, Dos Santos, Cedric, Stienen, Sabine, Friedrich, Matthias, Lutteropp, Michael, Nagorsen, Dirk, Wellbrock, Jasmin, Fiedler, Walter
Опубликовано в: Oncogene (2018)

Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

по Gottschlich, Adrian, Thomas, Moritz, Grünmeier, Ruth, Lesch, Stefanie, Rohrbacher, Lisa, Igl, Veronika, Briukhovetska, Daria, Benmebarek, Mohamed-Reda, Vick, Binje, Dede, Sertac, Müller, Katharina, Xu, Tao, Dhoqina, Dario, Märkl, Florian, Robinson, Sophie, Sendelhofert, Andrea, Schulz, Heiko, Umut, Öykü, Kavaka, Vladyslav, Tsiverioti, Christina Angeliki, Carlini, Emanuele, Nandi, Sayantan, Strzalkowski, Thaddäus, Lorenzini, Theo, Stock, Sophia, Müller, Philipp Jie, Dörr, Janina, Seifert, Matthias, Cadilha, Bruno L., Brabenec, Ruben, Röder, Natalie, Rataj, Felicitas, Nüesch, Manuel, Modemann, Franziska, Wellbrock, Jasmin, Fiedler, Walter, Kellner, Christian, Beltrán, Eduardo, Herold, Tobias, Paquet, Dominik, Jeremias, Irmela, von Baumgarten, Louisa, Endres, Stefan, Subklewe, Marion, Marr, Carsten, Kobold, Sebastian
Опубликовано в: Nat Biotechnol (2023)