High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells

High mobility group box 1 (HMGB1) is a non-histone protein which is predominantly localised in the cell nucleus. However, stressed, dying, injured or dead cells can release this protein into the extracellular matrix passively. In addition, HMGB1 release was observed in cancer and immune cells where...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Teo Hansen Selnø, Anette, Schlichtner, Stephanie, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Berger, Steffen M., Klenova, Elena, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8255966/
https://ncbi.nlm.nih.gov/pubmed/34234778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.675731
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