Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer

Here we describe the establishment and characterization of an AR+, PSMA+, ERG+, PTEN(−/−), CHD1(+/−) patient-derived xenograft (PDX) model termed ‘C5’, which has been developed from a 60 years old patient suffering from castration-resistant prostate cancer (CRPC). The patient underwent radical prost...

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Publicado no:Sci Rep
Main Authors: Lange, Tobias, Oh-Hohenhorst, Su Jung, Joosse, Simon A., Pantel, Klaus, Hahn, Oliver, Gosau, Tobias, Dyshlovoy, Sergey A., Wellbrock, Jasmin, Feldhaus, Susanne, Maar, Hanna, Gehrcke, Renate, Kluth, Martina, Simon, Ronald, Schlomm, Thorsten, Huland, Hartwig, Schumacher, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277427/
https://ncbi.nlm.nih.gov/pubmed/30510249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35695-8
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