CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells

We investigated the functional role of CEACAM1 in a spontaneous metastasis xenograft model of human melanoma in scid mice using BRAF wildtype MeWo cells with and without RNAi mediated knockdown of CEACAM1. Tumors from the xenograft model were subjected to whole genome expression analysis and metasta...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Wicklein, Daniel, Otto, Benjamin, Suling, Anna, Elies, Eva, Lüers, Georg, Lange, Tobias, Feldhaus, Susanne, Maar, Hanna, Schröder-Schwarz, Jennifer, Brunner, Georg, Wagener, Christoph, Schumacher, Udo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082866/
https://ncbi.nlm.nih.gov/pubmed/30089785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30338-4
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