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Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer
The heterodimeric laminin receptor α6β4 integrin plays a central role in the promotion of tumor cell growth, invasion, and organotropic metastasis. As an overproduction of the integrin is often linked to a poor prognosis, the inhibition of integrin α6β4 binding to laminin is of high therapeutical in...
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| Publicado no: | Mol Ther Nucleic Acids |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5014452/ https://ncbi.nlm.nih.gov/pubmed/26978578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2016.10 |
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