Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer

Immune checkpoints are intensively investigated as targets in cancer therapy. T-cell immunoreceptor with immunoglobulin (Ig) and ITIM domains (TIGIT) and its ligand poliovirus receptor (PVR) are recently emerging as novel promising targets in immunotherapy. Here, we show that high expression of PVR...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Stamm, Hauke, Oliveira-Ferrer, Leticia, Grossjohann, Eva-Maria, Muschhammer, Jana, Thaden, Vanessa, Brauneck, Franziska, Kischel, Roman, Müller, Volkmar, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844319/
https://ncbi.nlm.nih.gov/pubmed/31741778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1674605
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